Zoloft is an effective antidepressant with less potential for drowsiness than many other antidepressants, but it is not without its side effects (Turner, and Phelon, 2022 Ahmadpanah et al., 2019). It is believed that this rebalancing is the main action by which Zoloft helps people with anxiety, depression, and other disorders. It is this blocking of certain reuptake pathways, which helps to rebalance chemicals in the brain. SSRIs are thought to work by preventing the reuptake of serotonin by nerves, leading to an increase in serotonin concentrations within the nerve synapse (space between two nerves) (Yoham and Casadesus, 2022). Zoloft belongs to a group of medicines called Selective Serotonin Reuptake Inhibitors (SSRIs). The small steps add up and before long, you can discontinue medications altogether.Zoloft, with the generic name of Sertraline, is a commonly prescribed medication to treat depression, anxiety disorders, obsessive compulsive disorders and other emotionally induced stress disorders. A small reduction in dose rarely produces noticeable difference in sleep quality. The alternative is to slowly reduce the dose over a period of time (e.g. The bad nights caused by withdrawal lead many people to promptly resume use of the sleep medications. The fitful night is often caused by the discontinuation itself and usually does not reflect the underlying insomnia. An abrupt discontinuation of a sleep medication can cause a very fitful sleep on the first night or two after the discontinuation. Most newer sleep medications don't cause physical dependence but they can cause psychological dependence. However, individuals who have used sleep medications for a long period of time and wish to discontinue need to do so gradually and under the supervision of a physician. It is not necessary to discontinue sleep medication in order to benefit from CBTI. This means that their dose and purity are not monitored. The FDA does not regulate herbs and supplements. These remedies include herbs, such as valerian, and supplements, such as melatonin and L-tryptophan. Some people use over-the-counter medications, which usually contain antihistamines, or natural remedies for insomnia. These medications are usually prescribed at doses that are lower than what is required for the treatment of depression and they do not lead to tolerance or drug dependence. The most common antidepressants prescribed for sleep are Trazodone, Doxepine, and Elavil. For example, a sedating antidepressant medication is often prescribed to help with insomnia. Sometimes doctors prescribe a medication that is sedating even though it was not specifically developed to help with sleep. It affects the melatonin receptor in the brain. It has a very different mechanism of action. Ramelteon is another new sleep medication. Because of their safety profile and their lower potential for dependence, some medications in this class are approved by the FDA for continuous long-term use. Grogginess in the morning occurs when a sleep medication is metabolized slowly, and it's still active upon waking up in the morning. This happens because people differ in how they metabolize the medications. Some people experience grogginess in the morning even with sleep medications from this newer class. They're called "non-benzodiazepines", a confusing name given that they still operate by acting on the benzodiazepine receptors. Therefore, these newer sleep medications are safer and have lower potential for dependence and fewer side effects. Most of these newer medications work on the benzodiazepine receptors in the brain, but do it more selectively than the medications in the benzodiazepine class. In addition, some medications in this class can produce a "hangover" or grogginess the next day.įor these reasons, newer sleep medications have been developed and approved by the FDA. Benzodiazepines are generally recommended for short-term use because tolerance and dependence can develop. Other benzodiazepine medications approved by the FDA for the treatment of anxiety, such as Lorazepam, Clonazepam, and Alprazolam, are sometimes prescribed for insomnia as well. The following five medications, listed in alphabetical order, are approved by the FDA for the treatment of insomnia: These medications are older and have a higher potential for dependency. One class of sleep medication is called benzodiazepines. The discussion is organized by classes of medication. Below is a brief discussion of medications that are commonly used for sleep. These are called hypnotic medications or sleep medications. The Food and Drug Administration (FDA) has approved certain medications for the treatment of insomnia.
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